Finally, an EFFECTIVE non-opioid, non-invasive way to treat Chronic Pain

Scrambler Therapy's 80%-90% effectiveness in treating chronic neuropathic and oncologic pain gives you an unparalleled ability to care for your patients

Introducing Cutting-Edge Advancement in Chronic Pain Relief: Scrambler Therapy® Technology

  • Scrambler Therapy® ST-5A Technology is a revolutionary electroanalgesia device

  • Uses a biophysical (instead of biochemical) approach to treat chronic pain.

  • Transmits a “no pain” message to the surface receptors via disposable electrodes

  • Remodels the pain system to convey a message of “no pain” to the central nervous system.

As Seen in:

"80-90% of patients have a favorable response," states

The New England Journal of Medicine, July 2023

Scrambler Therapy® Technology Effective Chronic Pain Relief

Gives Hope to Patients with No Adverse Side Effects.

Discover a Wide Variety of Indications for Use

*Note: Scrambler Therapy is effective in treating most types of neuropathic and oncologic pain. Diagnosis listed to the right are some examples that Scrambler Therapy can treat. Book a call to explore diagnosis not listed.

Indications for Use

  • Chronic neuropathic pain

  • Chronic opioid-resistant pain

  • Chronic oncologic pain

Diagnosis Able to Treat:*

  • Complex Regional Pain Syndrome (CRPS)

  • Pancreas and abdominal cancer pain

  • Post-herpetic pain (shingles pain)

  • Bone metastases

  • Spinal cord stenosis

  • Post-mastectomy pain

  • Chemotherapy-induced Peripheral Neuropathy (CIPN)

  • Chronic Cancer Pain

  • Chronic Neuropathic Pain

  • Failed Back Surgery Syndrome (FBSS)

  • Sciatic and Lumbar Pain

  • Post herpetic Neuralgia (PHN)

  • Brachial Plexus Neuropathy

  • Low Back Pain (LBP)

  • Chronic Neuropathic Pain Opioid Addiction

  • Endometriosis

Understand the Treatment Behind Our

Solution for Chronic Pain

  • Employs 5 artificial neurons connected to electrodes to treat multiple pain areas simultaneously

  • By overriding the pain signal with a “no pain” signal to the brain, it scrambles (recodes) the neurons, reducing the patient’s pain level to zero regardless of the initial pain intensity and type

  • The treatment protocol typically includes 10 consecutive sessions over two weeks

  • Each session is ~45 minutes each

  • Booster sessions are provided as needed

  • Use is restricted to physicians (MD/DO) or to other qualified health care professionals under the direct supervision of a physician

Insights from Medical Experts

Hear What Doctors Have to Say About Our Exceptional Medical Device

 "It's effective, it's non-invasive, it reduces opioid use

substantially and it can be PERMANENT."

- Thomas Smith, M.D., professor of oncology and medicine at the

Johns Hopkins University School of Medicine

Listen to Dr Salahadin Abdi, MD, head of pain management at MD Anderson Cancer Center who led some of the clinical trial locations share his insight:

For more clinical information, please visit:

Your Patients Will Love Scrambler Therapy Too!

"For over 22 years, right hip pain plagued me due to Osteoarthritis. Medications like Norco® and a Fentanyl Patch left me sluggish and drugged. When the pain spread to my back and hands, meds weren't an option anymore. My doctor mentioned Scrambler Therapy®. After 6 months of waiting, I tried it. To my disbelief, the first treatment relieved my pain. My fingers went from claw like to functional, and life became manageable again. I restore antiques using my hands daily, and Scrambler Therapy® changed everything. Boosters make me feel even better. It's like a miracle—I've regained "ME." I cycle, ski, and live fully."

Gloria B. / Sandy, OR

"After my second session of Scrambler Therapy, I was at home and got up from a chair and got halfway across a room before I realized what I was doing. I Didn’t have any pain. I Didn’t struggle. I Didn’t grab my cane. I Didn’t think that was ever going to be possible again in my life.”

Tom / Portland, OR

"My chronic pain was so intense I lost my will to live. Over 30 doctors tried to alleviate the pain, but they could only provide slight, temporary relief. Over a two year timespan I went to over 350 medical visits, and had so many tests, injections, and nerve blocks I lost count. Then I learned of Scrambler Therapy. It sounded too good to be true given all the disappointments - I didn't believe there could be anything that could help. After 3 treatments I could walk normally again. By the end of the 10th treatment my pain was gone. Scrambler Therapy treatments, quite literally, saved my life."

Connor C. / McKinney, TX

“Had no hope of getting relief from the diabetic neuropathy in my feet. Now the pain,

burning and sensitivity is gone. Amazing.”

Bill / Portland, OR

"I felt so hopeless and helpless with my daughters chronic pain that was leaving her debilitated. Every option seemed worse than the next…surgery…possible addiction…drugs that would reduce her ability to live her life normally. We refused them all and we’re determined to grind it out with PT in hopes the pain would subside. We heard about scrambler therapy around 8 months into her ordeal. I was all for it…she was not. She was understandably afraid of it making her worse and also of me having paid the cost of it and it not working. Finally she agreed to at least give it a try. At first it really didn’t seem to be her answer. She experienced some relief, but it was minimal and short lived. We were encouraged by the stories of others success however so we decided to stick it out a while longer. On day nine while on the machine my daughter looked up and said that her pain was a “zero”. We got in the car to go home…both emotional. She looked me in the eye and said “it’s gone”. Chills ran down my spine. “What do you mean” I asked. “I mean it’s gone Mom. It’s not coming back.” She was right; it was gone and it has not come back. Scrambler therapy was nothing short of a miracle treatment for my daughter. There isn’t a day that goes by that I am not grateful for her having her life back pain free."

Connor C. / McKinney, TX

U.S. Locations

There are over 80 locations using Scrambler Therapy across the US today including:

16 Military and VA Hospitals

Research Hospitals: Mayo Clinic, Johns, Hopkins, MD Anderson, Cleveland Clinic, UCLA

Numerous Private Practices

(click on the map to open a Google Map)

EXCLUSIVE CONVENIENT TRAINING

IN YOUR OFFICE

FOR YOUR CONVENIENCE, WE OFFER 3 DIFFERENT OPTIONS FOR TRAINING:

"On-site" in your office - WE CATER TO YOU

BOISE, IDAHO

ROME, ITALY

Training is conducted over a 3-day period, ensuring each provider is given a wide variety of patients and diagnosis to treat. Both the science and the "art" of electrode placement and device functionality is covered in detail.

MAKE A PROFIT WITHIN THE FIRST 2 WEEKS!

Scrambler Therapy adds a new, billable procedure to your office with it's own CPT code. Our "Placement Agreement" structure offers a one-time, upfront cost of $4,999 for Training and Setup and a per-treatment fee, allows for your office to be profitable within weeks or months of starting treatments. Couple the Placement Agreement with the On-Site Training and you'll realize a profit Blog Postsafter the first 2 week!

A child undergoing chemotherapy treatment.

Can Scrambler Therapy™ Alleviate Chemotherapy-Induced Pain?

June 10, 20246 min read

Cancer treatment is hard enough without the added burden of relentless pain due to the side effects of chemotherapy. It can feel like one thing after another, and that life as the patient knew it is so far out of reach. The aches and extreme discomfort keep them from the things they love. But there is hope. Scrambler Therapy™ has an 80-90% effective rate for CIPN without invasive procedures or addictive prescription medications. We bet you it's the answer your patients have been searching for!

Understanding Chemotherapy-Induced Pain

Chemotherapy-induced pain is a harsh reality for many cancer patients. This type of pain can range from a persistent ache to intense, stabbing sensations and everything in between. It occurs because chemotherapy drugs, while targeting cancer cells, also damage healthy cells. The chemotherapy drugs cause axonal degeneration, where the nerve fibers get damaged. It can also cause demyelination, which is the loss of the protective covering of nerves. This damage disrupts normal nerve function, leading to pain signals being sent to the brain even when there's no actual injury. Inflammation from the drugs can also release cytokines, which heighten pain sensitivity. This makes the pain feel constant and unrelenting. 

This pain is notoriously difficult to treat because it doesn't respond well to standard pain relief methods. Prescription medications can offer some respite and are often a go-to from many doctors. But they come with their own set of side-effects, risks, expenses, and only treat the symptoms rather than the underlying problem. All of these compound into even more challenges and discomfort for the patient. 

What Is Scrambler Therapy™ and How Does It Work?

Scrambler Therapy™ (ST), originally known as Calmare Therapy, is an advanced, FDA-approved electro-analgesia therapy for the non-invasive treatment of chronic neuropathic and cancer pain.

Developed in Italy by Professor Giuseppe Marineo, this innovative therapy uses the ST-5A device, which sends non-painful electrical signals through surface electrodes placed on the skin near the area of pain. These signals travel along the same nerve pathways that usually carry pain signals to the brain.

The new age device uses five artificial neurons to deliver its therapeutic effects, differing greatly from the traditional gate control theory. This allows it the ability to disrupt the transmission of pain signals by introducing "non-pain" signals. It leverages neuroplasticity to retrain the brain's neural networks. Over multiple treatment sessions (typically ranging from 10 to 12), the brain begins to replace pain signals with these new ones, leading to an almost miraculous reduction in pain perception (and in most cases, full elimination).

Unlike TENS (Transcutaneous Electrical Nerve Stimulation), which masks the pain by stimulating the nerves, ST reprograms how the brain perceives the pain signals. It targets the C fibers, responsible for transmitting slow, chronic pain signals, effectively replacing the neural system’s interpretation of what is happening at the pain site.

Prestigious institutions such as MD Anderson Cancer Center, New England Journal of Medicine, Mayo Clinic, and Johns Hopkins have validated the effectiveness of Scrambler Therapy™. Between their research, case studies, and articles, it pays tribute to the powerful pain reduction in patients with chronic pain conditions. The therapy is safe enough for even children to use and offers almost immediate and long-lasting relief, addressing the root cause of pain at the neural level.

ST presents a promising solution for patients suffering from relentless chemotherapy-induced pain. It provides a non-invasive, risk-free, and cost-effective alternative to many traditional methods that can't effectively treat the condition. 

Benefits of Choosing Scrambler Therapy™ for Pain Relief

Scrambler Therapy™ offers a compelling option for those in need of relief from chronic pain, particularly chemotherapy-induced peripheral neuropathy (CIPN). ST provides several benefits that truly set it apart, showcasing just how impactful the treatment is.

  • Non-invasive treatment: Scrambler Therapy™ does not require surgery or injections, making it a less intimidating option for pain relief. Patients can skip the long recovery times and get back to the things they love even sooner!

  • Pain-free procedure: Patients typically do not find the treatment painful during their sessions, making it a more comfortable treatment option.

  • Rapid pain relief: Patients experience powerful pain reduction within the first few sessions, if not sooner, providing quick respite from chronic discomfort compared to traditional methods.

  • Addresses the root of the problem: Unlike many treatments that only mask pain, Scrambler Therapy™ reprograms pain signals at the neural level, tackling the underlying cause of chronic pain for stronger and longer results.

  • Long-lasting effects: A series of treatments offers sustained pain relief, reducing the need for ongoing medical interventions.

  • Safe for all ages: It is gentle enough to be used on patients of all ages, including children, without the risk of severe side effects.

  • Non-addictive and risk-free: Scrambler Therapy™ does not involve the use of drugs, eliminating the risk of addiction, cost, and other complications associated with long-term medication use.

  • Cost-effective: Compared to surgery and ongoing prescription costs, Scrambler Therapy™ is a more affordable option for long-term pain management.

  • Higher effectiveness rate than surgery: Scrambler Therapy™ has an 80-90% effective rate for chronic pain, providing better outcomes for certain chronic pain types than surgical options.

Scrambler Therapy™ provides a life-changing opportunity for those enduring the relentless pain of chemotherapy-induced neuropathy. It goes beyond masking symptoms to offer genuine and unparalleled relief other pain treatments can't for this type of pain. As their pain diminishes, patients regain the ability to perform daily activities, experience better sleep, an improved mood, and more. Scrambler Therapy™ restores hope to those who have felt the weight of hopelessness. It is a way to reclaim their lives and move forward with renewed strength and positivity.

Getting Started with Scrambler Therapy™

Getting started with Scrambler Therapy™ means more than just adding a new treatment into your practice. It's about reigniting the passion for patient care that brought you into the field to begin with. With over 80 locations across the US and growing, ST is making a noteworthy impact on chronic pain management that is easier to implement than you might think. 

From a business perspective, integrating ST can boost your practice's reputation for truly taking the steps toward innovative, compassionate care. It attracts new patients looking for advanced pain relief solutions and keeps existing patients engaged with your services. Your practice can become a much-needed new hope for those enduring relentless pain, reaffirming your commitment to compassionate care.

Training to implement Scrambler Therapy™ is designed to be comprehensive yet straightforward. It includes hands-on instruction on using the device, understanding patient protocols, and best practices for achieving optimal results. Your team will feel confident and well-prepared to deliver this transformative treatment. Our support team is also there for you to answer questions and guide you through the setup process. The model is inexpensive and doesn't require a huge amount of logistics or physical space within the practice.

By choosing Scrambler Therapy™, you are choosing to enhance your practice while reaffirming your commitment to improving the lives of those who need it most. 

Ready to get started? Reach out today to learn more and take the first step toward offering your patients a brighter, pain-free future!

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Houston, TX

Call 512-529-7269

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