No, in all the studies conducted in Europe and the United States, no serious adverse side effects (events) were reported. Some patients do experience a slight redness where the electrode was attached to thee patient's skin, which usually resolves within a short time after treatment
Scrambler Therapy and TENS medical devices are both in the category of "electroanalgesic devices." They both use send an electrical stimulation through wires and electrodes attached to the patients skin. The TENS unit has a square wave form targeting the A and Beta fibers in peripheral nerves and benefits generally stop when the device is turned off. Scrambler Therapy has artificial neurons that target the c fibers in affected dermatomes and replace the chronic pain signal with a non-pain waveform (signal). Benefits have been reported for weeks, months, and years. Please see the New England Journal of Medicine Review Article July 13th, 2023 for a side-by-side comparison of TENS and Scrambler Therapy
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