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Beyond Medication: Scrambler Therapy and CIPN Management

April 30, 20246 min read

Many aren't prepared for the challenges they'd face after receiving chemotherapy. The relentless discomfort of CIPN disrupts daily activities and clouds the relief that should come after surviving cancer. The typical treatments to try and ease CIPN can lead to a world of discomfort and addiction all in themselves, creating a negative feedback loop that feeds on your life. Scrambler Therapy introduces a hopeful alternative to this struggle, without the typical risks and side effects.

Living With CIPN

Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating side effect of cancer treatment. The chemicals designed to target and kill cancer cells can also cause collateral damage to the peripheral nerves. These nerves, which are responsible for sending sensory and motor signals to and from the brain, start to malfunction. The result is a confusing barrage of signals sent to the brain, leading to the pain and sensory disturbances that characterize CIPN.

Imagine the frustration when, after braving the turmoil of chemotherapy, a whole new challenge emerges: pain, burning, tingling, or numbness, primarily in the hands and feet. These symptoms are without a doubt uncomfortable but they are hugely disruptive, impacting the ability to perform everyday tasks and live a quality life.

For those living with this condition, the physical symptoms are just the start. The emotional toll of coping with CIPN can be equally challenging, as it adds another layer of stress and anguish to the already difficult recovery. For those who have survived cancer thanks to chemotherapy and are now faced with CIPN, it can feel hopeless, isolating, and unattainable to get back to everyday life. But we're here to shed light on the situation: it doesn't have to be this way. 

Typical Treatments and Medications for CIPN

The typical treatment options for chemotherapy-induced peripheral neuropathy (CIPN) can feel like trading one set of challenges for another. It can be hard to choose a 'good' option due to side effects and risks. It becomes even more difficult when faced with trying to choose a treatment option due to the side effects from a treatment already. 

When prescribed opioids for the severe pain, patients face the extreme risks behind the highly addictive medication. It can be that, or living life as a shell of yourself due to the pain. There is also the financial impact of long-term use to consider. While opioids do their job to dull the pain, they don't treat the actual cause of the issue. It just makes the pain tolerable. The high risk of dependency and endless costs can further complicate a patient's recovery and mindset. It can even draw a wedge between them and their families, isolating them more, or even needing rehabilitation in the long run.

For those considering nerve (lumbar) decompression surgery, the choice is still a gamble. The anticipation of surgery is marred by long waiting lists and the severe financial strain due to high costs. Medical debts have likely already piled high due to the chemotherapy treatments unless a fantastic insurance policy has safeguarded the family. The emotional toll of surgical failure and facing potential long recovery times can be equally overwhelming, as patients anxiously wonder if they will ever feel better.

The body doesn't always know when to shut off the anxiety, creating persistent ongoing symptoms, adding stress to an already challenging health situation.

Turning to antidepressants or anti-anxiety tablets to cope with the deep feelings of hopelessness, the isolation of chronic pain, and emotional distress seems like a no-brainer step. But these too come with a price. Side effects like weight gain, numbness, fatigue, suicidal thoughts, and addiction and more can feel like adding insult to injury, complicating an already difficult recovery process. So the question is still: what to do? When the pain is so bad it is robbing the ability to properly live, how do you choose the best of the worst? That’s when Scrambler Therapy comes in.

What is Scrambler Therapy? 

Scrambler Therapy, created by Neuroscientist Giuseppe Marineo in Italy, introduces a transformative approach to treating chronic pain. It is especially effective for chronic pain conditions like chemotherapy-induced peripheral neuropathy (CIPN). The current model (ST-5A) is a device that uses noninvasive technology to revise the way the body processes pain signals without the risk or side effects of drugs or surgery.

Scrambler Therapy's ability to retrain the brain's pain signals works through electrodes placed on the skin. These signals mimic normal nerve impulses, effectively re-educating the brain to recognize and process the pain. This technique is based on the principle of neuroplasticity—the brain’s ability to reorganize itself by forming new neural connections in response to new information or stimulation. Through regular sessions, Scrambler Therapy helps the brain recalibrate and diminish the pain signals, effectively reducing the pain experience.

Clinical studies and trials have demonstrated an 80-90% effectiveness rate in reducing pain through Scrambler Therapy, confirming its efficacy and reliability as a treatment method. Its accessibility, low cost, and immediate pain-reduction have made it life-changing for patients dealing with chronic pain conditions where traditional therapies have failed. It provides a viable alternative that avoids the adverse effects commonly associated with drugs and invasive procedures. 

Why Does Scrambler Therapy Work Well for CIPN Management? 

Scrambler Therapy's effectiveness in managing chemotherapy-induced peripheral neuropathy (CIPN) is enhanced by its targeted approach to electrode placement, which is critical for addressing the specific areas where CIPN patients experience the most intense discomfort. In CIPN, nerve damage due to chemotherapy typically manifests with severe pain in the hands and feet—areas dense with nerve endings that convey pain sensation to the brain.

The strategic placement of Scrambler Therapy’s electrodes around these key areas allows for precise intervention. This ensures that the new 'non-pain' signals have the most direct route to the affected nerve pathways, providing an optimal environment for neural retraining. 

This process diminishes the perception of pain and contributes to the gradual restoration of normal nerve function in the peripheral areas most affected by CIPN. This means you're treating the root issue instead of a bandaid treatment for the symptoms! After the treatment course, patients will be pain-free and see a huge improvement in sensation, regaining functional use of hands and feet again. This is life changing for getting back the small joys in life. Even daily tasks will feel like a true gift. And it really is, the gift of pain-free autonomy.

How to Access Scrambler Therapy

Access to Scrambler Therapy is expanding across the United States, making this innovative treatment more and more available to those suffering from severe pain. 

Over 80 locations nationwide, including prestigious institutions such as the Mayo Clinic, Johns Hopkins University, MD Anderson Cancer Center, Cleveland Clinic, and UCLA, offer Scrambler Therapy. Additionally, 16 Military and VA Hospitals and numerous private practices have also adopted this technology, recognizing its potent transformation for pain.

To find a Scrambler Therapy provider near you, click here to visit the map showcasing the USA locations.

If you are experiencing debilitating pain and looking for noninvasive treatment options, please talk to your doctor about accessing Scrambler Therapy. 

For doctors and medical professionals, incorporating Scrambler Therapy into your practice elevates the level of care you can provide.  Please contact us now with any questions, or speak to us about getting set up in your practice.


Whether you are a patient seeking relief or a healthcare provider aiming to enhance your treatment offerings, Scrambler Therapy presents a promising avenue worth exploring. 

We’re on a mission to help people live their best, pain-free lives. You can help by sharing this article and other content with your colleagues, friends, and family. 

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